The Wealth Index is based on a number of indicators of affluence including average household income and average net worth, but it also includes the value of material possessions and resources. It represents the wealth of the area relative to the national level. Values above or below 100 represent above-average wealth or below-average wealth compared to the national level.
| Name | County | Wealth Index | |
|---|---|---|---|
| 1. | Manderson-White Horse Creek Census Designated Place | Oglala Lakota | 19 |
| 2. | Spring Creek Census Designated Place | Todd | 19 |
| 3. | Oglala Census Designated Place | Oglala Lakota | 20 |
| 4. | Two Strike Census Designated Place | Todd | 21 |
| 5. | Parmelee Census Designated Place | Todd | 23 |
| 6. | Kyle Census Designated Place | Oglala Lakota | 23 |
| 7. | Antelope Census Designated Place | Todd | 25 |
| 8. | City of Mission | Todd | 25 |
| 9. | Town of Saint Francis | Todd | 26 |
| 10. | Wanblee Census Designated Place | Jackson | 26 |
| 11. | White Horse Census Designated Place | Todd | 26 |
| 12. | City of McLaughlin | Corson | 27 |
| 13. | Porcupine Census Designated Place | Oglala Lakota | 28 |
| 14. | Soldier Creek Census Designated Place | Todd | 28 |
| 15. | Rosebud Census Designated Place | Todd | 29 |
| 16. | North Eagle Butte Census Designated Place | Dewey | 29 |
| 17. | Fort Thompson Census Designated Place | Buffalo | 29 |
| 18. | City of Eagle Butte | Dewey | 32 |
| 19. | Lower Brule Census Designated Place | Lyman | 33 |
| 20. | Pine Ridge Census Designated Place | Oglala Lakota | 33 |
